Disease Agreement

Data availability: The authors shared the data in a Figshare public repository, available under this URL: figshare.com/articles/Data_set_from_agreement_between_CVD_risk_assessment_tools_in_UAE_study_xlsx/11406594. EADRA is a cost-sharing instrument between the government and the livestock sector, even in the event of an outbreak of epizootics. To describe the characteristics of the study population, descriptive statistics were provided for both quantitative and qualitative variables. The predicted 10-year cvD risks were calculated using the initial equations provided in the corresponding published work. CVD risk equations derived from original publications were calculated with an online application developed by the corresponding author. The online application is based on the R Shiny package and is freely accessible via the following link [comparecvdandguidelines.shinyapps.io/internal-private-test/]. Lin`s concordance correlation coefficients (CCCs) were calculated to measure the total degree of compliance and between each pair of risk assessment instruments [12,13]. The Lin concordance coefficient quantifies the degree of agreement between the tools at risk and is between -1 and 1, the limit being considered a perfect concordance. The rule of thumb for a good degree of compliance is a CCC value greater than 0.9 [14]. We also calculated the percentage of subjects assigned to the high-risk category according to the threshold indicated in the corresponding initial guidance document for each risk assessment instrument.

The thresholds used were 20% for WHO-MENA, 5% for SCORE-H, 7.5% for PCRE-W and PCRE-AA, 20% for fram-ATP and 20% for FRAM-LAB [5-8,10]. In this analysis, we also assessed the differences between the different risk assessment instruments by reporting rates of misclassification. Average risk estimates increased for all at-risk devices due to the inclusion of diabetics. However, overall compliance (0.49) between at-risk devices remained similar to that of patients without diabetes (0.50). Conclusions: Disease-specific criteria for DNR prescriptions have been developed to complement the general DNR guidelines for patients with hemispheric infarction and intracebraal hemorrhage during the first 2 weeks of stroke. A group of doctors has reached a significant agreement that patients with acute stroke should not be resuscitated if these specific criteria are met. Many factors could be at the root of the mismatch between the cvD risk assessment instruments in our study. One such factor is the risk classification threshold, which differs from an instrument. . . .